Tire microplastics are considered one of important microplastics, which is the second largest contributor of primary microplastics to marine environment on global scale. Tire microplastics mainly derive from tires used on roads even though tires are made to be highly wear-resistant, which are very easy to enter the urban water environments with the way of atmospheric settlement, rainwater, surface water flow, etc. Subsequently, they may accumulate in the landscape rivers and the construc...
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Metabolic diseases, such as obesity, diabetes and atherosclerosis, are the diseases with the highest morbidity and mortality worldwide. Disorders of extracellular microenvironmental signals in macrophages, such as inflammation, oxidative stress, and overnutrition, can induce dysfunction of macrophages and other surrounding cells, thereby promoting the occurrence and development of metabolic diseases. Previous studies have found that the exposure of oleate, a main fatty acid in food and h...
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