This project aims to fabricate a novel three dimensional (3D) electrospun nanofiber material and develop a solution to effectively remove trace antibiotics from the municipal wastewater, and to promote the improvement of quality of water environment in our country. We are planning to analyze the physiochemical properties of the typical antibiotics in the water body, and then select the polymers and/or inorganic precursors which have strong adsorption affinity towards the typical antibiotics for the electrospinning of nanofibers; After that, novel 3D nanofibers with fluffy structure will be fabricated through the liquid-assisted collection and the optimization of electrospinning parameters; Specific efforts will be made to develop the strategies to enhanced the mechanical strength of the 3D nanofibers and to improve the adsorption affinity towards the antibiotics. The adsorption performance and mechanism of the antibiotics will be investigated through adsorption column test and spectroscopy analysis. New adsorption column water treatment reactor will be designed according to the properties of the 3D nanofibers adsorbent, mathematical model will be developed to simulate the adsorption process. A new process for efficient elimination of trace antibiotics in municipal wastewater by “3D nanofiber column adsorption” will be developed. This project may provide promising new materials and methods for the efficient removal of trace pollutants from water.