A series of Fe-V-Ti oxide catalysts were prepared by a co-precipitation method, among which the Fe_0.1V_0.1TiOx catalyst showed the optimal NH₃-SCR performance and excellent SO₂ resistance. Fe_0.1V_0.1TiO_x achieved > 90% NOx conversion at 225–450 °C under a GHSV of 200,000 h^-1. When introducing SO₂ and H₂O to the SCR reaction for 24 h, the NOx conversion maintained a level above 93% at 250 °C. The Raman and Mossbauer spectra showed that FeVO₄ and Fe₂O₃ coexisted on the surface of TiO₂. In Fe-V-Ti catalysts, the charge interaction between Fe₂O₃ and FeVO₄ as well as the electronic inductive effect between Fe and V species resulted in the improvement of SCR activity and N₂ selectivity at high temperatures. The NH₃-SCR process on the Fe_0.1V_0.1TiO_x catalyst mainly followed the Eley-Rideal (E–R) reaction mechanism with gaseous NO reacting with adsorbed NH₃ adsorbed species.